A Review of the management of adult patients with cryptococcal meningitis at Mthatha hospital complex, Mthatha, Eastern Cape, South Africa

Olufunso Sogbanmu, Prof U Lalloo


Rationale for the study

This study is to explore the prevalence and the profiles of patients infected with cryptococcal meningitis and more importantly, the different aspects of the management on cryptococcal meningitis in a rural area of Eastern Cape, South Africa.

  • Cryptococcal meningitis is a common opportunistic infection in the era of Human Immunodeficiency infection and understanding the management of cryptoccocal meningitis is an important public health goal that will ensure better care of patients with HIV/AIDS (4, 12)
  • Morbidity and mortality are increased with late detection, and so insight into the common presentation could help increase the index of suspicion of attending clinicians (17)
  • Studies have been done to review the treatment of cryptococcal meningitis outside South Africa and within the country (15, 23, 25). There is dearth of information addressing the management of cryptococcal meningitis in rural area of the Eastern Cape, South Africa.
  • Also if the condition is poorly managed, mortality and morbidity may be increased.