The impact of HIV and Intestinal parasite co-infection on nutritional and immune status of adults receiving nutritional supplements in KwaZulu-Natal.

Zilungile Mkhize-Kwitshana


Intestinal parasite infection, malnutrition and HIV have a convergent distribution in sub-Saharan Africa. South Africa is one of the countries with highest prevalence of HIV/AIDS. This country also has high helminth infections especially among school age children and preschoolers as well as adults in resource-limited settings. However, the public health significance of co-infection with HIV and helminthes and its relationship to malnutrition and immune deficiency is poorly researched.


The study aims to define the baseline immune and nutritional status of adults who are co-infected with HIV and helminth infections. The second aim is to assess the effect of a three month nutritional supplementation on improving the nutrition, weight, macro and micronutrient status in dually and singly infected adults compared to their uninfected counterparts and their baseline.


Adults 18 years and above will be recruited from HIV Counseling and Testing sites in two districts of KwaZulu Natal. Their HIV and parasite infection status, nutritional and immune profiles will be determined at baseline and three months after monthly nutritional supplementation. Differences in groups classified by HIV and helminth co-infection and non infection will be analysed.