The Prevalence of Hepatitis B virus infection in infants : KwaZulu-Natal, South africa

Nokukhanya Mdlalose, Raveen Parboosing


This research seeks to shed light on the prevalence of HBV infection in the infant population in KwaZulu-Natal. It will also describe how this prevalence differs in the HIV infected and uninfected child, as these two viral infections have similar routes of transmission as well as some common therapeutic measures. There is a vaccine available for the prevention of HBV, and it is given as part of the expanded programme on immunisation in South Africa since 1995. Response to immunization may be adversely affected by HIV co-infection. Optimizing the diagnosis of HBV using dried blood samples will be beneficial as this is a cost effective and safer method, and can be used for routine diagnosis of HBV from the same sample currently used for the diagnosis of HIV in infants.