To investigate the intracellular survival in macrophages of S (susceptible), MDR and XDR Mycobacterium tuberculosis isolates in aiming to determine differences among these isolates and associate these with disease progression

Jessica Thompson, Willem Sturm

Abstract


The degree of survival of Mycobacterium tuberculosis isolates in human macrophages is a virulence characteristic that is an independent variable which determining disease progression in patients with tuberculosis.