An assessment of the efficacy of HIV post exposure prophylaxis following childhood sexual assault

Sithokozile Lindiwe Buthelezi, N McKerrow


Post exposure prophylaxis is able to prevent HIV infection following occupational exposure to the virus. Theoretically it should, if administered timeously and for a sufficient period, be able to prevent HIV infection following sexual assault.


The clinical records of children presenting to Edendale and Grey’s Hospital following sexual assault will be reviewed to determine the compliance of both healthcare worker and patients with the PEP protocol as well as the efficacy of the PEP regimen in preventing HIV transmission. The demographic characteristics of the children, the nature of the sexual assault, clinical findings and adherence to the protocol will be assessed to determine factors associated with failure of the protocol.