THE MATERNAL AND FETAL OUTCOMES OF HUMAN IMMUNODEFICIENCY VIRUS INFECTED AND NON-INFECTED OBSTETRIC PATIENTS ADMITTED TO INTENSIVE CARE UNITS IN THE PIETERMARITZBURG HOSPITAL COMPLEX

Nnabuike Chibuoke Ngene, Jack Moodley

Abstract


The aim of this study is to determine the outcomes of HIV infected and non-infected obstetric patients admitted to in intensive care units, in the Pietermaritzburg area. This study will show whether HIV sero-status influences outcomes. The study sites will be at Edendale and Grey’s hospitals. Data will be extracted prospectively from the hospital charts of all pregnant women admitted to the intensive care unit (ICU) facilities in both hospitals, over a 10-months period. Each patient will be categorized as having low or high GRAMPT risk stratification score. The outcomes of patients’ treatment will be collated and analyzed descriptively. The primary maternal outcome will be death. The primary fetal outcomes are babies born alive, stillbirth, Apgar score in 5 minutes and birth weight. The secondary maternal outcomes are the duration of stay in ICU, ventilation of patient, duration of ventilation, use of inotropes and blood/blood products, and whether patient had tracheostomy, laparotomy/re-laparotomy, re-intubation, re-admission into ICU or dialysis. The secondary fetal outcome is whether the delivery of fetus will be undertaken to facilitate maternal care.